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Persons with one pathogenic variant tend to have milder disease (manifest mainly by fever and abdominal symptoms) than persons with two pathogenic variants.

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For treatment of gout flares: You should have decreased pain, tenderness, or swelling.

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While gout is caused by uric acid crystals, pseudogout is the result of crystals formed from calcium pyrophosphate dihydrate (CPPD).

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OA and no gout were strongly correlated with both synovial fluid IL-1 level and OA severity, they noted.

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It is well recognized as a valid therapy in acute flares of gouty arthritis, familial Mediterranean fever (FMF), Behçet's disease, and recurring pericarditis with effusion.

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Chapter 4: Concluding Thoughts about You, Your Health and Gout.

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